A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications

• Published in: Molecules (Basel, Switzerland) Vol. 25; no. 8; p. 1909
• Main Authors: Kerru, Nagaraju, Gummidi, Lalitha, Maddila, Suresh, Gangu, Kranthi Kumar, Jonnalagadda, Sreekantha B.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 20.04.2020; MDPI AG
• Subjects: biological activities; current trends; Drug Design; Drug Development; Heterocyclic Compounds - chemistry; Heterocyclic Compounds - pharmacology; Humans; Molecular Structure; Nitrogen - chemistry; nitrogen-based heterocycles; Review; Structure-Activity Relationship; nitrogen-based heterocycles; biological activities; structure-activity relationship; current trends

The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much...