Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment - Grillone, Agostina; Battaglini, Matteo; Moscato, Stefania; Mattii, Letizia; de Julián Fernández, César; Scarpellini, Alice; Giorgi, Mario; Sinibaldi, Edoardo; Ciofani, Gianni (Nanomedicine (London, England), 2019)
Keywords: Antineoplastic Agents - chemistry; Antineoplastic Agents - therapeutic use; Apoptosis; Biological Transport; Blood-Brain Barrier; Brain cancer; Cancer therapies; Cell cycle; Cell Line, Tumor; Cell Survival - drug effects; Chemotherapy; Cytotoxicity; Drug Carriers - chemistry; Drug efficacy; Drug Liberation; dynamic fluidic models; Glioblastoma - drug therapy; glioblastoma multiforme; Humans; Imidazoles - chemistry; Imidazoles - therapeutic use; Kinases; Kinetics; Lipids; Lipids - chemistry; Magnetic fields; magnetic targeting; Magnetite Nanoparticles - chemistry; Nanoparticles; nutlin-3a; Particle Size; Physicochemical properties; Piperazines - chemistry; Piperazines - therapeutic use; Proteins; Senescence; solid lipid nanoparticles; Surface Properties; Tumors; glioblastoma multiforme; dynamic fluidic models; blood–brain barrier; magnetic targeting; nutlin-3a; solid lipid nanoparticles