Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review

• Published in: Frontiers in pharmacology Vol. 13; p. 964005
• Main Authors: Haseeb, Abdul, Faidah, Hani Saleh, Alghamdi, Saleh, Alotaibi, Amal F., Elrggal, Mahmoud Essam, Mahrous, Ahmad J., Abuhussain, Safa S. Almarzoky, Obaid, Najla A., Algethamy, Manal, AlQarni, Abdullmoin, Khogeer, Asim A., Saleem, Zikria, Iqbal, Muhammad Shahid, Ashgar, Sami S., Radwan, Rozan Mohammad, Mutlaq, Alaa, Fatani, Nayyra, Sheikh, Aziz
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 21.09.2022
• Subjects: beta-Lactams; carbapenems; cephalosporins; dose optimization; penicillins; Pharmacology; carbapenems; beta-Lactams; dose optimization; cephalosporins; penicillins

Background: β-lactams remain the cornerstone of the empirical therapy to treat various bacterial infections. This systematic review aimed to analyze the data describing the dosing regimen of β-lactams. Methods: Systematic scientific and grey literature was performed in accordance with Preferred Item...