Perturbation on gut microbiota impedes the onset of obesity in high fat diet-induced mice

• Published in: Frontiers in endocrinology (Lausanne) Vol. 13; p. 795371
• Main Authors: Yu, Zhongjia, Yu, Xiang-Fang, Kerem, Goher, Ren, Pei-Gen
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 09.08.2022
• Subjects: Animals; bioinformatic pipelines; Blood Glucose; Diabetes Mellitus, Type 2 - complications; Diet, High-Fat - adverse effects; Endocrinology; Gastrointestinal Microbiome; jejunal microbiota; Metabolic Diseases - complications; Mice; Mice, Obese; obesity; Obesity - etiology; Obesity - metabolism; perturbation; T2DM; bioinformatic pipelines; T2DM; jejunal microbiota; perturbation; obesity

High-calorie intake has become one of the most common causes of dietary obesity, which eventually develops into type 2 diabetes mellitus (T2DM). Microbiota, along with the length of the gastrointestinal tract, is related to metabolic disorders, but its shifts and following impact on metabolic disord...