Identification and molecular characterization of the mammalian α-kleisin RAD21L

• Published in: Cell cycle (Georgetown, Tex.) Vol. 10; no. 9; pp. 1477 - 1487
• Main Authors: Gutiérrez-Caballero, Cristina, Herrán, Yurema, Sánchez-Martín, Manuel, Suja, José Ángel, Barbero, José Luis, Llano, Elena, Pendás, Alberto M.
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.05.2011
• Subjects: Amino Acid Sequence; Animals; Binding; Biology; Bioscience; Calcium; Cancer; Cell; Cell Cycle Proteins - chemistry; Cell Cycle Proteins - genetics; Chromosomal Proteins, Non-Histone - chemistry; Chromosomal Proteins, Non-Histone - genetics; Cohesins; Conserved Sequence; Cycle; DNA-Binding Proteins - chemistry; DNA-Binding Proteins - genetics; HEK293 Cells; Humans; Landes; Male; Meiosis - genetics; Mice; Molecular Sequence Data; Nuclear Proteins - chemistry; Nuclear Proteins - genetics; Organogenesis; Phosphoproteins - chemistry; Phosphoproteins - genetics; Protein Structure, Tertiary - genetics; Proteins; Sequence Homology, Amino Acid; Testis - chemistry; Testis - physiology

Meiosis is a fundamental process that generates new combinations between maternal and paternal genomes and haploid gametes from diploid progenitors. Many of the meiosis-specific events stem from the behavior of the cohesin complex (CC), a proteinaceous ring structure that entraps sister chromatids u...