Role of PI3K in the Progression and Regression of Atherosclerosis

• Published in: Frontiers in pharmacology Vol. 12; p. 632378
• Main Authors: Zhao, Yunyun, Qian, Yongjiang, Sun, Zhen, Shen, Xinyi, Cai, Yaoyao, Li, Lihua, Wang, Zhongqun
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 09.03.2021
• Subjects: atherosclerosis; drug therapy; Pharmacology; PI3K; plaque; signaling pathways; atherosclerosis; plaque; drug therapy; signaling pathways; PI3K

Phosphatidylinositol 3 kinase (PI3K) is a key molecule in the initiation of signal transduction pathways after the binding of extracellular signals to cell surface receptors. An intracellular kinase, PI3K activates multiple intracellular signaling pathways that affect cell growth, proliferation, mig...