Identification of Transmembrane Protein in Prostate Cancer by the Escherichia coli Ampicillin Secretion Trap: Expression of CDON Is Involved in Tumor Cell Growth and Invasion

• Published in: Pathobiology (Basel) Vol. 78; no. 5; pp. 277 - 284
• Main Authors: Hayashi, Tetsutaro, Oue, Naohide, Sakamoto, Naoya, Anami, Katsuhiro, Oo, Htoo Zarni, Sentani, Kazuhiro, Ohara, Shinya, Teishima, Jun, Matsubara, Akio, Yasui, Wataru
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.09.2011
• Subjects: Ampicillin; Anti-Bacterial Agents; Biomarkers, Tumor - analysis; Blotting, Western; Cell Adhesion Molecules - genetics; Cell Adhesion Molecules - metabolism; Cell growth; E coli; Escherichia coli; Gene Expression Profiling; Gene Library; Genetic Techniques; Humans; Male; Membranes; Neoplasm Invasiveness - genetics; Neoplasm Invasiveness - pathology; Original Paper; Prostate cancer; Prostatic Neoplasms - genetics; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Proteins; Real-Time Polymerase Chain Reaction; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - metabolism; Tumors; Prostate cancer; Escherichia coli ampicillin secretion trap; CDON

Aims: Prostate cancer (PCa) is one of the most common malignancies worldwide. Genes expressed only in cancer tissue, and especially related to proteins located on the cell membrane, will be useful molecular markers for diagnosis and may also be good therapeutic targets. The aim of this study was to...