A Micro-Platinum Wire Biosensor for Fast and Selective Detection of Alanine Aminotransferase

• Published in: Sensors (Basel, Switzerland) Vol. 16; no. 6; p. 767
• Main Authors: Thuy, Tran Nguyen Thanh, Tseng, Tina T-C
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.05.2016; MDPI
• Subjects: Acids; Alanine; alanine aminotransferase; Alanine Transaminase - analysis; Alanine Transaminase - metabolism; amperometric; Biosensing Techniques - methods; biosensor; Biosensors; Cellulose acetate; Chromatography; Constants; Dehydrogenases; Dopamine; Electrical measurements; Electrodes; Enzymes; glutamate oxidase; Liver diseases; microelectrode; Oxidase; Platinum - chemistry; Polypyrroles; Sensors; Voltammetry; Wire; alanine aminotransferase; microelectrode; biosensor; glutamate oxidase; amperometric

In this study, a miniaturized biosensor based on permselective polymer layers (overoxidized polypyrrole (Ppy) and Nafion(®)) modified and enzyme (glutamate oxidase (GlutOx)) immobilized micro-platinum wire electrode for the detection of alanine aminotransferase (ALT) was fabricated. The proposed ALT...