The amino acid sequence of Limulus C-reactive protein. Evidence of polymorphism

• Published in: The Journal of biological chemistry Vol. 261; no. 22; pp. 10456 - 10465
• Main Authors: Nguyen, N Y, Suzuki, A, Boykins, R A, Liu, T Y
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 05.08.1986; American Society for Biochemistry and Molecular Biology
• Subjects: Alpha-Globulins; Amino Acid Sequence; Amyloid; Analytical, structural and metabolic biochemistry; Animals; Biological and medical sciences; Biological Evolution; C-Reactive Protein - genetics; Cloning, Molecular; Cricetinae; Disulfides; DNA - genetics; Fundamental and applied biological sciences. Psychology; Glucosamine - metabolism; Glycoproteins; Horseshoe Crabs - analysis; Humans; Mesocricetus; Peptide Fragments; Polymorphism, Genetic; Proteins; Rabbits; Limulus; Primary structure; Anti C protein; Polymorphism

The amino acid sequence, the positions of the disulfide bonds, and the site of glycosylation for the three subunits of Limulus C-reactive proteins (CRPs) 1.1, 1.4, and 3.3 have been established. The three subunits were shown to exist approximately in equimolar amount and are tightly associated. The...