Neural correlates of trait anxiety in fear extinction
Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulat...
Saved in:
| Published in | Psychological medicine Vol. 41; no. 4; pp. 789 - 798 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge, UK
Cambridge University Press
01.04.2011
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction.
Thirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T). Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety.
Analysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses.
This study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders. |
|---|---|
| AbstractList | Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction. Thirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T). Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety. Analysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses. This study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsitivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders. Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction. Thirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T). Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety. Analysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses. This study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders. Background. Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction. Method. Thirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T), Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety. Results. Analysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses. Conclusions. This study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsitivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders. Adapted from the source document. Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction.BACKGROUNDFear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction.Thirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T). Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety.METHODThirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T). Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety.Analysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses.RESULTSAnalysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses.This study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders.CONCLUSIONSThis study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders. Background: Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory prefrontal cortex (PFC). In this study we investigated whether individual differences in trait anxiety affect amygdala and dorsal anterior cingulate cortex (dACC) activation during fear conditioning and extinction. Method: Thirty-two healthy subjects were investigated by functional magnetic resonance imaging (fMRI) at 3 T while performing a cued fear-conditioning task. All participants completed the trait version of the State-Trait Anxiety Inventory (STAI-T). Activations of the amygdala and the dACC were examined with respect to the effects of trait anxiety. Results: Analysis of the fMRI data demonstrated enhanced activation in fear-related brain areas, such as the insula and the ACC, during both fear conditioning and extinction. Activation of the amygdala appeared only during the late acquisition phase whereas deactivation was observed during extinction. Regression analyses revealed that highly trait-anxious subjects exhibited sustained amygdala activation and reduced dACC involvement during the extinction of conditioned responses. Conclusions: This study reveals that high levels of trait anxiety are associated with both increased amygdala activation and reduced dACC recruitment during the extinction of conditioned fear. This hyper-responsitivity of the amygdala and the deficient cognitive control during the extinction of conditioned fear in anxious subjects reflect an increased resistance to extinct fear responses and may thereby enhance the vulnerability to developing anxiety disorders. [PUBLICATION ABSTRACT] |
| Author | Sehlmeyer, C. Pyka, M. Schöning, S. Pfleiderer, B. Zwitserlood, P. Schiffbauer, H. Kugel, H. Heindel, W. Konrad, C. Dannlowski, U. Arolt, V. |
| Author_xml | – sequence: 1 givenname: C. surname: Sehlmeyer fullname: Sehlmeyer, C. organization: 1Department of Psychiatry, University Hospital of Muenster, Germany – sequence: 2 givenname: U. surname: Dannlowski fullname: Dannlowski, U. organization: 1Department of Psychiatry, University Hospital of Muenster, Germany – sequence: 3 givenname: S. surname: Schöning fullname: Schöning, S. organization: 1Department of Psychiatry, University Hospital of Muenster, Germany – sequence: 4 givenname: H. surname: Kugel fullname: Kugel, H. organization: 3Department of Clinical Radiology, University Hospital of Muenster, Germany – sequence: 5 givenname: M. surname: Pyka fullname: Pyka, M. organization: 1Department of Psychiatry, University Hospital of Muenster, Germany – sequence: 6 givenname: B. surname: Pfleiderer fullname: Pfleiderer, B. organization: 3Department of Clinical Radiology, University Hospital of Muenster, Germany – sequence: 7 givenname: P. surname: Zwitserlood fullname: Zwitserlood, P. organization: 4Department of Psychology, University of Muenster, Germany – sequence: 8 givenname: H. surname: Schiffbauer fullname: Schiffbauer, H. organization: 3Department of Clinical Radiology, University Hospital of Muenster, Germany – sequence: 9 givenname: W. surname: Heindel fullname: Heindel, W. organization: 3Department of Clinical Radiology, University Hospital of Muenster, Germany – sequence: 10 givenname: V. surname: Arolt fullname: Arolt, V. organization: 1Department of Psychiatry, University Hospital of Muenster, Germany – sequence: 11 givenname: C. surname: Konrad fullname: Konrad, C. email: Carsten.Konrad@med.uni-marburg.de organization: 1Department of Psychiatry, University Hospital of Muenster, Germany |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23924625$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/20550755$$D View this record in MEDLINE/PubMed |
| BookMark | eNqN0U1LHTEUBuBQlHq1_QHdlEEoXY3NyXeWIlYLYhdt10Mm90QiczM2yYD--87gtYJi6yqL87wHTt59spPGhIR8AHoEFPSXH5RyzixooJQCE-YNWYFQtjVWmx2yWsbtMt8j-6Vcz4aDYG_JHqNSUi3lishLnLIbGj_mjIOrWJoxNDW7WBuXbiPWuyamJqDLDd7WmHyNY3pHdoMbCr7fvgfk19fTnyfn7cX3s28nxxetF0rW1lBAxhkGi4YFK0CKgEpJhjqItbKB94J6HoxYWwW9o1xwY6BnoJ00gfED8vl-700ef09YareJxeMwuITjVDpLNUir2f-lUYYxYOoVUnJrOQMzy8Mn8nqccpoPXpDiwvIFfdyiqd_gurvJcePyXffwxTP4tAWueDeE7JKP5dFxy4Rii4N75_NYSsbwlwDtlrq7Z3XPGf0k42N1S0NLg8M_k3ybdJs-x_UVPh73cuoPquq3-g |
| CODEN | PSMDCO |
| CitedBy_id | crossref_primary_10_1093_scan_nsy073 crossref_primary_10_1016_j_biopsych_2012_06_003 crossref_primary_10_1016_j_neuroscience_2014_10_004 crossref_primary_10_1016_j_neubiorev_2012_05_011 crossref_primary_10_1111_bph_13090 crossref_primary_10_1038_s41380_025_02940_2 crossref_primary_10_3758_s13415_015_0365_4 crossref_primary_10_1016_j_neuroimage_2012_03_063 crossref_primary_10_1038_srep00308 crossref_primary_10_3389_fpsyg_2022_917876 crossref_primary_10_1038_s41398_019_0415_8 crossref_primary_10_2174_1573404817666210405141000 crossref_primary_10_1002_da_22605 crossref_primary_10_1016_j_neuroimage_2021_118157 crossref_primary_10_1093_scan_nsx025 crossref_primary_10_1016_j_neubiorev_2018_03_015 crossref_primary_10_1002_da_22583 crossref_primary_10_1038_s41386_020_00936_w crossref_primary_10_1111_j_1469_8986_2011_01298_x crossref_primary_10_1002_brb3_232 crossref_primary_10_1146_annurev_clinpsy_050212_185542 crossref_primary_10_1016_j_biopsycho_2015_07_010 crossref_primary_10_1016_j_biopsycho_2021_108084 crossref_primary_10_3389_fnbeh_2016_00010 crossref_primary_10_1016_j_biopsycho_2016_05_001 crossref_primary_10_1159_000501024 crossref_primary_10_1016_j_nlm_2018_06_001 crossref_primary_10_1177_0956797612443830 crossref_primary_10_1016_j_mhpa_2014_10_001 crossref_primary_10_1002_da_22156 crossref_primary_10_1038_s41598_021_98023_7 crossref_primary_10_1016_j_biopsycho_2013_01_011 crossref_primary_10_1016_j_neubiorev_2017_02_026 crossref_primary_10_1038_s44159_023_00156_1 crossref_primary_10_1007_s10566_022_09718_5 crossref_primary_10_1016_j_euroneuro_2018_11_328 crossref_primary_10_1016_j_bbr_2012_05_036 crossref_primary_10_1016_j_jad_2011_12_026 crossref_primary_10_1002_mpr_1560 crossref_primary_10_1016_j_pnpbp_2011_05_002 crossref_primary_10_1016_j_ijpsycho_2022_09_001 crossref_primary_10_1016_j_bandc_2024_106225 crossref_primary_10_1016_j_neuroimage_2011_12_048 crossref_primary_10_1038_npp_2011_73 crossref_primary_10_3389_fpsyg_2017_01654 crossref_primary_10_1007_s00702_012_0811_1 crossref_primary_10_1038_mp_2012_172 crossref_primary_10_1016_j_neuroimage_2019_116427 crossref_primary_10_1016_j_neuroimage_2019_116428 crossref_primary_10_1016_j_neubiorev_2023_105292 crossref_primary_10_1016_j_neuroimage_2021_118819 crossref_primary_10_1371_journal_pone_0048665 crossref_primary_10_1016_j_biopsych_2017_06_016 crossref_primary_10_1038_s41398_020_01177_7 crossref_primary_10_1007_s00406_012_0319_6 crossref_primary_10_1016_j_ijpsycho_2019_09_014 crossref_primary_10_1093_scan_nsr095 crossref_primary_10_2174_1874440001307010041 crossref_primary_10_1016_j_neubiorev_2018_03_002 crossref_primary_10_1038_s41598_025_94790_9 crossref_primary_10_1016_j_biopsycho_2019_107744 crossref_primary_10_1016_j_neuroimage_2016_03_024 crossref_primary_10_3724_SP_J_1042_2019_00268 crossref_primary_10_1016_j_nlm_2018_07_002 crossref_primary_10_1007_s00406_012_0329_4 crossref_primary_10_1007_s11682_017_9772_1 crossref_primary_10_1016_j_brat_2020_103800 crossref_primary_10_1016_j_neubiorev_2019_06_029 crossref_primary_10_1186_1471_2202_13_4 crossref_primary_10_1016_j_nlm_2017_09_005 crossref_primary_10_7202_1040038ar crossref_primary_10_1016_j_pnpbp_2018_08_014 crossref_primary_10_1080_02699931_2016_1265485 crossref_primary_10_1176_appi_focus_20210024 crossref_primary_10_1016_j_ntt_2021_106973 crossref_primary_10_1016_j_biopsych_2011_12_027 crossref_primary_10_1038_s41467_023_39825_3 crossref_primary_10_1016_j_neubiorev_2018_12_013 crossref_primary_10_1016_j_ijpsycho_2020_04_012 crossref_primary_10_1080_17470919_2015_1091037 crossref_primary_10_1038_mp_2011_96 crossref_primary_10_1002_hbm_22112 crossref_primary_10_1016_j_neuroimage_2012_09_030 crossref_primary_10_1186_s13587_015_0019_8 crossref_primary_10_1007_s12350_020_02101_8 crossref_primary_10_1111_psyp_13961 crossref_primary_10_1016_j_neubiorev_2018_10_013 crossref_primary_10_1016_j_neubiorev_2020_09_016 crossref_primary_10_1016_j_neubiorev_2012_10_012 crossref_primary_10_1093_cercor_bhad236 crossref_primary_10_1038_mp_2015_88 crossref_primary_10_3758_s13415_020_00814_4 crossref_primary_10_1007_s00429_015_1085_9 crossref_primary_10_1016_j_neuropsychologia_2015_08_007 crossref_primary_10_1016_j_neuroimage_2012_02_039 crossref_primary_10_1371_journal_pone_0105054 crossref_primary_10_3389_fnbeh_2016_00222 crossref_primary_10_12677_ASS_2022_113104 crossref_primary_10_1007_s00787_019_01389_3 crossref_primary_10_1093_scan_nst127 crossref_primary_10_1038_npp_2014_324 crossref_primary_10_1016_j_brainres_2014_01_025 crossref_primary_10_1017_S0954579417001626 crossref_primary_10_1016_j_nicl_2022_103060 crossref_primary_10_1017_S0033291716000477 crossref_primary_10_1016_j_jveb_2023_06_002 crossref_primary_10_1097_01_pra_0000416014_53215_86 crossref_primary_10_1080_02699931_2017_1370418 crossref_primary_10_7243_2055_3447_1_2 crossref_primary_10_1371_journal_pone_0109949 crossref_primary_10_1016_j_jad_2024_08_143 crossref_primary_10_1016_j_neuroimage_2015_07_034 crossref_primary_10_1093_scan_nsv139 crossref_primary_10_3109_10253890_2015_1117449 crossref_primary_10_1038_s41598_020_72007_5 crossref_primary_10_1111_desc_12260 crossref_primary_10_3389_fphar_2022_906639 crossref_primary_10_1016_j_biopsych_2015_12_010 crossref_primary_10_1016_j_neubiorev_2017_07_007 crossref_primary_10_1016_j_biopsych_2011_10_021 |
| Cites_doi | 10.1037/0735-7044.121.2.249 10.1016/S0301-0511(03)00053-X 10.1016/j.janxdis.2003.09.001 10.1016/j.paid.2008.09.003 10.1006/nimg.2001.0978 10.1037/1082-989X.7.1.19 10.1038/nn1314 10.1016/j.biopsych.2006.06.004 10.1017/S0033291704003290 10.1006/nimg.2001.1004 10.1016/j.brat.2007.02.012 10.1016/j.neuron.2004.08.042 10.1016/j.neuroimage.2010.01.031 10.1016/j.biopsych.2006.06.022 10.1037/0021-843X.105.4.637 10.1097/01.wnr.0000186596.64458.76 10.1038/nn.2242 10.1016/0304-3940(93)90241-C 10.1016/j.biopsycho.2005.11.008 10.1016/j.tics.2007.05.008 10.1016/j.neuropsychologia.2008.05.005 10.1016/S0896-6273(00)80475-4 10.1037/0735-7044.114.4.671 10.1016/S0165-1781(01)00228-1 10.1146/annurev.neuro.24.1.897 10.1016/S0896-6273(02)01064-4 10.1038/nn.2222 10.1002/ana.410360107 10.1097/01.wnr.0000186599.66243.50 10.1016/S0959-4388(00)00078-7 10.1523/JNEUROSCI.2550-04.2004 10.1002/hbm.20483 10.1523/JNEUROSCI.2265-08.2008 10.1016/j.comppsych.2007.12.004 10.1111/j.1460-9568.2009.06624.x 10.1016/j.neuroimage.2005.12.031 10.1002/mrm.1910330508 10.1146/annurev.clinpsy.1.102803.143916 10.1016/j.biopsych.2006.03.010 10.1016/j.biopsych.2005.10.012 10.1371/journal.pone.0005865 10.1093/cercor/bhp155 10.1126/science.284.5422.1979 10.1016/j.neuroimage.2006.08.021 10.1093/cercor/12.4.376 10.1016/j.brat.2004.10.007 10.1176/appi.ajp.2007.07030504 10.1017/S1461145708008973 10.1017/S0033291708003516 10.1016/j.pscychresns.2007.08.002 10.1016/j.neuron.2004.12.006 10.1016/S1364-6613(00)01483-2 10.1523/JNEUROSCI.23-25-08800.2003 10.1016/j.neuroimage.2004.01.012 10.1016/0005-7916(94)90063-9 10.1038/86110 10.1007/s002210100733 10.1016/0028-3932(71)90067-4 10.1037/0021-843X.116.3.612 |
| ContentType | Journal Article |
| Copyright | Copyright © Cambridge University Press 2010 2015 INIST-CNRS |
| Copyright_xml | – notice: Copyright © Cambridge University Press 2010 – notice: 2015 INIST-CNRS |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 0-V 3V. 7QJ 7QP 7QR 7RV 7TK 7X7 7XB 88E 88G 8FD 8FI 8FJ 8FK 8G5 ABUWG AFKRA ALSLI AZQEC BENPR CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ GUQSH HEHIP K9. KB0 M0S M1P M2M M2O M2S MBDVC NAPCQ P64 PHGZM PHGZT PJZUB PKEHL POGQB PPXIY PQEST PQQKQ PQUKI PRINS PRQQA PSYQQ Q9U 7X8 7U1 C1K |
| DOI | 10.1017/S0033291710001248 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Social Sciences Premium Collection ProQuest Central (Corporate) Applied Social Sciences Index & Abstracts (ASSIA) Calcium & Calcified Tissue Abstracts Chemoreception Abstracts Nursing & Allied Health Database Neurosciences Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) Technology Research Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Research Library ProQuest Central (Alumni) ProQuest Central UK/Ireland Social Science Premium Collection ProQuest Central Essentials ProQuest ProQuest One ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library Sociology Collection ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) ProQuest Health & Medical Collection Medical Database Psychology Database (ProQuest) ProQuest - Research Library Sociology Database (ProQuest) Research Library (Corporate) Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest Sociology & Social Sciences Collection ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Social Sciences ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic Risk Abstracts Environmental Sciences and Pollution Management |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology Research Library Prep ProQuest Central Student ProQuest Central Essentials Sociology & Social Sciences Collection ProQuest Central China Health Research Premium Collection Health & Medical Research Collection Chemoreception Abstracts ProQuest Central (New) ProQuest Sociology ProQuest Medical Library (Alumni) Social Science Premium Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection Sociology Collection Health Research Premium Collection (Alumni) Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Social Sciences Premium Collection ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest One Academic (New) Technology Research Database ProQuest One Academic Middle East (New) ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing Research Library (Alumni Edition) Applied Social Sciences Index and Abstracts (ASSIA) ProQuest Central Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Research Library ProQuest Sociology Collection ProQuest One Social Sciences ProQuest Central Basic ProQuest Nursing & Allied Health Source ProQuest Psychology Journals (Alumni) ProQuest Medical Library ProQuest Psychology Journals ProQuest Central (Alumni) MEDLINE - Academic Risk Abstracts Environmental Sciences and Pollution Management |
| DatabaseTitleList | Risk Abstracts MEDLINE Applied Social Sciences Index and Abstracts (ASSIA) MEDLINE - Academic ProQuest One Psychology |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central Database Suite (ProQuest) url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitleAlternate | Trait anxiety and fear extinction C. Sehlmeyer et al. |
| EISSN | 1469-8978 |
| EndPage | 798 |
| ExternalDocumentID | 2275329721 20550755 23924625 10_1017_S0033291710001248 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- -1D -1F -2P -2V -E. -~6 -~N .FH .GJ .XZ 0-V 08P 09C 09E 0E1 0R~ 123 29P 3V. 4.4 41~ 53G 5RE 5VS 6~7 74X 74Y 7RV 7X7 7~V 88E 8FI 8FJ 8G5 8R4 8R5 9M5 AAAZR AABES AABWE AACJH AAGFV AAKTX AAMNQ AARAB AASVR AATMM AAUIS AAUKB AAWTL AAYEP ABBXD ABBZL ABGDZ ABITZ ABIVO ABJNI ABKKG ABLJU ABQTM ABQWD ABROB ABTCQ ABUWG ABVFV ABVKB ABVZP ABWCF ABXAU ABZCX ABZUI ACBMC ACDLN ACETC ACGFO ACGFS ACHQT ACIMK ACIWK ACPRK ACRPL ACUIJ ACYZP ACZBM ACZUX ADAZD ADBBV ADDNB ADFEC ADFRT ADKIL ADNMO ADOVH ADOVT ADVJH AEBAK AEBPU AEHGV AEMFK AEMTW AENCP AENEX AENGE AEPLO AEYHU AEYYC AFFNX AFFUJ AFKQG AFKRA AFLOS AFLVW AFUTZ AFZFC AGABE AGJUD AGLWM AHIPN AHLTW AHMBA AHQXX AHRGI AIGNW AIHIV AIOIP AISIE AJ7 AJCYY AJPFC AJQAS AKZCZ ALIPV ALMA_UNASSIGNED_HOLDINGS ALSLI ALVPG ANPSP AQJOH ARABE ARALO ARZZG ASOEW ATUCA AUXHV AYIQA AZGZS AZQEC BBLKV BCGOX BENPR BESQT BGHMG BJBOZ BKEYQ BLZWO BMAJL BPHCQ BQFHP BRIRG BVXVI C0O C45 CAG CBIIA CCPQU CCQAD CCUQV CDIZJ CFAFE CFBFF CGQII CHEAL CJCSC COF CS3 DC4 DOHLZ DU5 DWQXO EBS EGQIC EJD EX3 F5P FA8 FYUFA GNUQQ GUQSH HEHIP HG- HMCUK HST HZ~ H~9 I.6 I.7 I.9 IH6 IOEEP IOO IS6 I~P J36 J38 J3A J5H JHPGK JQKCU JVRFK KAFGG KCGVB KFECR L7B L98 LHUNA LW7 M-V M1P M2M M2O M2S M7~ M8. N4W NAPCQ NEJ NIKVX NMFBF NZEOI O9- OMB OMC OMH OVD OYBOY P2P PQQKQ PROAC PSQYO PSYQQ Q2X RCA RIG ROL RR0 S6- S6U SAAAG SY4 T9M TEORI UAP UCJ UKHRP UT1 UU6 VVN WFFJZ WH7 WOW WQ3 WXU WYP YOC YZZ ZCA ZDLDU ZGI ZJOSE ZMEZD ZXP ZYDXJ ~V1 AAKNA AAYXX ABHFL ABXHF ACEJA ACOZI ADPDF AGQPQ AKMAY ANOYL CITATION IPYYG PHGZM PHGZT AAFWJ IQODW PJZUB POGQB PPXIY PRQQA CGR CUY CVF ECM EIF NPM 7QJ 7QP 7QR 7TK 7XB 8FD 8FK FR3 K9. MBDVC P64 PKEHL PQEST PQUKI PRINS Q9U 7X8 7U1 C1K |
| ID | FETCH-LOGICAL-c465t-801e232ef9e82f94154fe6652e7f4d69f3b40c3f84d961ba0343881b217a58f23 |
| IEDL.DBID | 7X7 |
| ISSN | 0033-2917 1469-8978 |
| IngestDate | Tue Aug 05 10:20:36 EDT 2025 Fri Jul 11 16:47:50 EDT 2025 Fri Jul 11 02:26:58 EDT 2025 Fri Jul 25 06:54:58 EDT 2025 Mon Jul 21 06:02:52 EDT 2025 Mon Jul 21 09:17:15 EDT 2025 Tue Jul 01 04:15:41 EDT 2025 Thu Apr 24 22:59:33 EDT 2025 Tue Jan 21 06:21:22 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Keywords | ACC amygdala extinction trait anxiety conditioning fear Human Affect affectivity Amygdala Healthy subject Extinction Central nervous system Basal ganglion Emotion emotionality Personality Experimental study Metabolism Nuclear magnetic resonance imaging Encephalon Fear Young adult Anxiety Conditioning Amygdaloid nucleus Functional imaging |
| Language | English |
| License | https://www.cambridge.org/core/terms CC BY 4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c465t-801e232ef9e82f94154fe6652e7f4d69f3b40c3f84d961ba0343881b217a58f23 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| PMID | 20550755 |
| PQID | 853634938 |
| PQPubID | 35753 |
| PageCount | 10 |
| ParticipantIDs | proquest_miscellaneous_907159722 proquest_miscellaneous_868221262 proquest_miscellaneous_853993218 proquest_journals_853634938 pubmed_primary_20550755 pascalfrancis_primary_23924625 crossref_primary_10_1017_S0033291710001248 crossref_citationtrail_10_1017_S0033291710001248 cambridge_journals_10_1017_S0033291710001248 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2011-04-01 |
| PublicationDateYYYYMMDD | 2011-04-01 |
| PublicationDate_xml | – month: 04 year: 2011 text: 2011-04-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Cambridge, UK |
| PublicationPlace_xml | – name: Cambridge, UK – name: Cambridge – name: England |
| PublicationTitle | Psychological medicine |
| PublicationTitleAlternate | Psychol Med |
| PublicationYear | 2011 |
| Publisher | Cambridge University Press |
| Publisher_xml | – name: Cambridge University Press |
| References | Tottenham (S0033291710001248_ref065) 2002; 14 Spielberger (S0033291710001248_ref061) 1972; 1 S0033291710001248_ref043 S0033291710001248_ref042 S0033291710001248_ref041 S0033291710001248_ref040 Wittchen (S0033291710001248_ref068) 1997 S0033291710001248_ref007 S0033291710001248_ref006 S0033291710001248_ref049 S0033291710001248_ref005 S0033291710001248_ref004 S0033291710001248_ref048 S0033291710001248_ref003 S0033291710001248_ref047 S0033291710001248_ref046 S0033291710001248_ref002 S0033291710001248_ref001 S0033291710001248_ref044 Carlson (S0033291710001248_ref012) 2010 S0033291710001248_ref032 S0033291710001248_ref031 S0033291710001248_ref030 Quirk (S0033291710001248_ref052) 2003; 23 S0033291710001248_ref039 Spielberger (S0033291710001248_ref063) 1983 S0033291710001248_ref038 S0033291710001248_ref037 S0033291710001248_ref036 S0033291710001248_ref035 S0033291710001248_ref034 S0033291710001248_ref033 S0033291710001248_ref019 Pavlov (S0033291710001248_ref045) 1927 S0033291710001248_ref021 S0033291710001248_ref020 S0033291710001248_ref064 S0033291710001248_ref060 S0033291710001248_ref028 S0033291710001248_ref027 S0033291710001248_ref026 Laux (S0033291710001248_ref029) 1981 S0033291710001248_ref025 S0033291710001248_ref024 S0033291710001248_ref023 S0033291710001248_ref022 S0033291710001248_ref066 S0033291710001248_ref009 S0033291710001248_ref008 Wang (S0033291710001248_ref067) 2007; 87 S0033291710001248_ref054 S0033291710001248_ref010 S0033291710001248_ref053 S0033291710001248_ref051 S0033291710001248_ref050 S0033291710001248_ref018 S0033291710001248_ref017 S0033291710001248_ref016 S0033291710001248_ref015 Spielberger (S0033291710001248_ref062) 1979 S0033291710001248_ref059 S0033291710001248_ref058 S0033291710001248_ref014 S0033291710001248_ref013 S0033291710001248_ref057 S0033291710001248_ref056 S0033291710001248_ref055 S0033291710001248_ref011 |
| References_xml | – ident: S0033291710001248_ref022 doi: 10.1037/0735-7044.121.2.249 – ident: S0033291710001248_ref030 doi: 10.1016/S0301-0511(03)00053-X – ident: S0033291710001248_ref013 doi: 10.1016/j.janxdis.2003.09.001 – ident: S0033291710001248_ref048 doi: 10.1016/j.paid.2008.09.003 – ident: S0033291710001248_ref066 doi: 10.1006/nimg.2001.0978 – ident: S0033291710001248_ref033 doi: 10.1037/1082-989X.7.1.19 – ident: S0033291710001248_ref021 doi: 10.1038/nn1314 – ident: S0033291710001248_ref054 doi: 10.1016/j.biopsych.2006.06.004 – ident: S0033291710001248_ref009 doi: 10.1017/S0033291704003290 – ident: S0033291710001248_ref050 doi: 10.1006/nimg.2001.1004 – ident: S0033291710001248_ref007 doi: 10.1016/j.brat.2007.02.012 – ident: S0033291710001248_ref046 doi: 10.1016/j.neuron.2004.08.042 – ident: S0033291710001248_ref032 doi: 10.1016/j.neuroimage.2010.01.031 – ident: S0033291710001248_ref001 doi: 10.1016/j.biopsych.2006.06.022 – volume-title: State-Trait-Angstinventar (Testmappe mit Handanweisung, Fragebogen STAI-G Form X 1 und Fragebogen STAI-G Form X 2 year: 1981 ident: S0033291710001248_ref029 – ident: S0033291710001248_ref014 doi: 10.1037/0021-843X.105.4.637 – ident: S0033291710001248_ref043 doi: 10.1097/01.wnr.0000186596.64458.76 – ident: S0033291710001248_ref005 doi: 10.1038/nn.2242 – ident: S0033291710001248_ref037 doi: 10.1016/0304-3940(93)90241-C – ident: S0033291710001248_ref028 doi: 10.1016/j.biopsycho.2005.11.008 – ident: S0033291710001248_ref004 doi: 10.1016/j.tics.2007.05.008 – ident: S0033291710001248_ref023 doi: 10.1016/j.neuropsychologia.2008.05.005 – ident: S0033291710001248_ref026 doi: 10.1016/S0896-6273(00)80475-4 – ident: S0033291710001248_ref019 doi: 10.1037/0735-7044.114.4.671 – ident: S0033291710001248_ref003 doi: 10.1016/S0165-1781(01)00228-1 – ident: S0033291710001248_ref034 doi: 10.1146/annurev.neuro.24.1.897 – ident: S0033291710001248_ref041 doi: 10.1016/S0896-6273(02)01064-4 – ident: S0033291710001248_ref025 doi: 10.1038/nn.2222 – ident: S0033291710001248_ref055 doi: 10.1002/ana.410360107 – ident: S0033291710001248_ref053 doi: 10.1097/01.wnr.0000186599.66243.50 – ident: S0033291710001248_ref010 doi: 10.1016/S0959-4388(00)00078-7 – year: 2010 ident: S0033291710001248_ref012 article-title: Feeling anxious: anticipatory amygdalo-insular response predicts the feeling of anxious anticipation publication-title: Social Cognitive and Affective Neuroscience – ident: S0033291710001248_ref006 doi: 10.1523/JNEUROSCI.2550-04.2004 – ident: S0033291710001248_ref040 doi: 10.1002/hbm.20483 – ident: S0033291710001248_ref057 doi: 10.1523/JNEUROSCI.2265-08.2008 – ident: S0033291710001248_ref058 doi: 10.1016/j.comppsych.2007.12.004 – ident: S0033291710001248_ref027 doi: 10.1111/j.1460-9568.2009.06624.x – ident: S0033291710001248_ref039 doi: 10.1016/j.neuroimage.2005.12.031 – ident: S0033291710001248_ref020 doi: 10.1002/mrm.1910330508 – ident: S0033291710001248_ref035 doi: 10.1146/annurev.clinpsy.1.102803.143916 – ident: S0033291710001248_ref051 doi: 10.1016/j.biopsych.2006.03.010 – ident: S0033291710001248_ref060 doi: 10.1016/j.biopsych.2005.10.012 – ident: S0033291710001248_ref059 doi: 10.1371/journal.pone.0005865 – ident: S0033291710001248_ref056 doi: 10.1093/cercor/bhp155 – ident: S0033291710001248_ref049 doi: 10.1126/science.284.5422.1979 – ident: S0033291710001248_ref064 doi: 10.1016/j.neuroimage.2006.08.021 – ident: S0033291710001248_ref044 doi: 10.1093/cercor/12.4.376 – volume-title: Conditioned Reflexes year: 1927 ident: S0033291710001248_ref045 – ident: S0033291710001248_ref031 doi: 10.1016/j.brat.2004.10.007 – volume: 87 start-page: 971 year: 2007 ident: S0033291710001248_ref067 article-title: Functional magnetic resonance imaging of whole brain related to motor preparation and execution [in Chinese] publication-title: Zhonghua Yi Xue Za Zhi – ident: S0033291710001248_ref018 doi: 10.1176/appi.ajp.2007.07030504 – ident: S0033291710001248_ref015 doi: 10.1017/S1461145708008973 – volume-title: SCID-I. Structured Clinical Interview for DSM-IV [in German] year: 1997 ident: S0033291710001248_ref068 – ident: S0033291710001248_ref002 doi: 10.1017/S0033291708003516 – volume-title: Manual for the State-Trait Anxiety Inventory year: 1983 ident: S0033291710001248_ref063 – ident: S0033291710001248_ref016 doi: 10.1016/j.pscychresns.2007.08.002 – ident: S0033291710001248_ref017 doi: 10.1016/j.neuron.2004.12.006 – ident: S0033291710001248_ref011 doi: 10.1016/S1364-6613(00)01483-2 – volume: 23 start-page: 8800 year: 2003 ident: S0033291710001248_ref052 article-title: Stimulation of medial prefrontal cortex decreases the responsiveness of central amygdala output neurons publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.23-25-08800.2003 – volume: 1 volume-title: Anxiety: Current Trends in Theory and Research year: 1972 ident: S0033291710001248_ref061 – ident: S0033291710001248_ref038 doi: 10.1016/j.neuroimage.2004.01.012 – ident: S0033291710001248_ref008 doi: 10.1016/0005-7916(94)90063-9 – ident: S0033291710001248_ref047 doi: 10.1038/86110 – ident: S0033291710001248_ref024 doi: 10.1007/s002210100733 – volume-title: Understanding Stress and Anxiety year: 1979 ident: S0033291710001248_ref062 – ident: S0033291710001248_ref042 doi: 10.1016/0028-3932(71)90067-4 – ident: S0033291710001248_ref036 doi: 10.1037/0021-843X.116.3.612 – volume: 14 start-page: S74 year: 2002 ident: S0033291710001248_ref065 article-title: Categorization of facial expressions in children and adults: establishing a larger stimulus set publication-title: Journal of Cognitive Neuroscience |
| SSID | ssj0013142 |
| Score | 2.3856888 |
| Snippet | Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the inhibitory... Background: Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the... Background. Fear conditioning involves the amygdala as the main neural structure for learning fear responses whereas fear extinction mainly activates the... |
| SourceID | proquest pubmed pascalfrancis crossref cambridge |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 789 |
| SubjectTerms | Adult Affectivity. Emotion Amygdala - physiopathology Anxiety Anxiety - physiopathology Anxiety - psychology Arousal - physiology Biological and medical sciences Brain Brain Mapping Conditioning Conditioning, Classical - physiology Cortex Extinction Extinction, Psychological - physiology Fear Fear & phobias Fear - physiology Female Fundamental and applied biological sciences. Psychology Gyrus Cinguli - physiopathology Human Humans Image Processing, Computer-Assisted Learning. Memory Magnetic Resonance Imaging Male Nerve Net - physiopathology NMR Nuclear magnetic resonance Oxygen - blood Personality Inventory Personality. Affectivity Prefrontal Cortex - physiopathology Psychological extinction Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Temperament - physiology Trait anxiety Young Adult |
| Title | Neural correlates of trait anxiety in fear extinction |
| URI | https://www.cambridge.org/core/product/identifier/S0033291710001248/type/journal_article https://www.ncbi.nlm.nih.gov/pubmed/20550755 https://www.proquest.com/docview/853634938 https://www.proquest.com/docview/853993218 https://www.proquest.com/docview/868221262 https://www.proquest.com/docview/907159722 |
| Volume | 41 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_8ABFE_HZORx58EottmqTNk6hsiKCIONjbSNoEBtJNN8E_37u26xjiXttLSS_X3O9y1_sBXBqlXYa3gpT7LBBG-sDGygTOqNxxK43OKVB8flGPffE0kIO6Nmdal1XO98Ryo87HGZ2R36BbUbHQcXo7-QyINIqSqzWDxjpsUucyquhKBskiiRCJqll4SVcWJfOkZtkxGi_Stag8iiH2n0VrhSUXtTMxU9SWr2gu_sehpT_q7cFuDSTZXbXy-7DmigPYeq5T5Ycgqe0GCmREv_FBiJKNPSNGiBkzxQ-VarJRwTxaOsMNelSUPzgcQb_XfX94DGqOhCATSs7IwTgERc5rh9rW6I6Fd0pJ7hIvcqV9bEWYxT4VuVaRNWEs4hShKkYiRqaex8ewUYwLdwosE1ZYk-iIK3yIlVY6jAcF96FJBTeiBdeNioa1pU-HVZVYMvyj0RaEcy0Os7rfOL3kx6ohV82QSdVsY5VwZ2lpmhEcIZ_AsK4F7flaLabbmFELWHMXvyhKk5jCjb9LEQRtCH1WiCjEVagn_r-IRuyGwRpHkZPKThYTDKmJnJRnKyfYhu3q_JqqhM5hY_b17S4QAM1spzTzDmzed19e334B0oT-RQ |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3daxQxEB_KFbQg4lf1rNY86Iu4dDc7yW0eRPxoudreIdJC37bJbgKFsnd6V9Q_yv_Rmf06ivTe-ppMluzMJPObTDID8Npq4wvqijIZigitCpFLtY281aWXTllTsqM4merxKX49U2cb8Ld7C8PXKrs9sd6oy1nBZ-R7ZFZ0iibNPsx_RFw0ioOrXQWNRiuO_J9f5LEt3h9-IfG-kfJg_-TzOGqLCkQFarXkHdkTivDBeJqeIfuFwWutpB8FLLUJqcO4SEOGpdGJs3GKaUbYjqC7VVngPAe0429iSp7MADY_7U-_fV-FLRJs0pPXBdKSURdGrXNUUyO3JfXhD9cbWiVzuGYU783tguQTmsIaNyPf2gIePID7LXQVHxtdewgbvnoEdyZtcP4xKE70QQQFF_y4ZAwrZkFwDYqlsNVvvhwqLioRiIuCTMJFVT-peAKnt8LAbRhUs8o_A1GgQ2dHJpGaPuKUU548UJQhthlKi0N417Mob9fWIm_upY3y_zg6hLjjYl60Gc75Jy_XDXnbD5k36T3WEe9eE00_QhLIRHIkh7DTyWo13V5xhyD6XlrDHJixlZ9d1SQEEwlsrSHRhOSIT_JmEkNokdxDSSRPGz1ZTTDmtHVKPV87wVdwd3wyOc6PD6dHO7DVnJ7zHaUXMFj-vPIvCX4t3W6r9ALOb3ud_QM7BTlp |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3dSxwxEB_EghSkVNvaq195aF_Exd1skt08iIh6-FHFB4V72ya7CQiyd3on1T_N_86Z_TpEvDdfk8mSncwkv8lMZgB-G6Vdjl1Byn0eCCN9YGNlAmdU4biVRhdkKJ5fqONrcTqQgzl4bt_CUFhluydWG3UxzOmOfAePFRULHac7vomKuDzs743uAiogRY7WtppGLSFn7uk_Wm_j3ZNDXOo_nPePrg6Og6bAQJALJSe0OztEFM5rh1PVeJYJ75SS3CVeFEr72Iowj30qCq0ia8JYxCniPITxRqaech7g7v8piWVEKpYMkqkDIxJ1ovKqVFqUtA7VKls1NlJbVF0DUeWhaVqHV8fj4siMcaV8XWLjfQxcnYX9r_ClAbFsv5a6JZhz5TIsnDdu-m8gKeUHEuRU-uOW0CwbekbVKCbMlI8UJspuSuaRhwxZfFNWjyu-w_WHsO8HzJfD0v0ElgsrrEl0xBV-xEorHdqigvvQpIIb0YPtjkVZo2XjrI5QS7I3HO1B2HIxy5tc5_STt7OGbHVDRnWij1nEG6-WphvBEW4KNCl7sNqu1XS6nQj3gHW9qM3kojGlGz5UJAgYEXbNIFGI6ZBP_H0SjbgRDUWOJCu1nEwnGFICOyl_zZzgJiygdmV_Ty7OVuFzfY1OwUprMD-5f3DriMMmdqOSeAb_PlrFXgDX2Tw5 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Neural+correlates+of+trait+anxiety+in+fear+extinction&rft.jtitle=Psychological+medicine&rft.au=Sehlmeyer%2C+C&rft.au=Dannlowski%2C+U&rft.au=Sch%C3%B6ning%2C+S&rft.au=Kugel%2C+H&rft.date=2011-04-01&rft.issn=1469-8978&rft.eissn=1469-8978&rft.volume=41&rft.issue=4&rft.spage=789&rft_id=info:doi/10.1017%2FS0033291710001248&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0033-2917&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0033-2917&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0033-2917&client=summon |