Functional Connectivity Dynamics Altered of the Resting Brain in Subjective Cognitive Decline

• Published in: Frontiers in aging neuroscience Vol. 14; p. 817137
• Main Authors: Wei, Yi-Chia, Kung, Yi-Chia, Huang, Wen-Yi, Lin, Chemin, Chen, Yao-Liang, Chen, Chih-Ken, Shyu, Yu-Chiau, Lin, Ching-Po
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.06.2022
• Subjects: Aging Neuroscience; dynamic functional connectivity; dynamics; mdALFF; preclinical dementia; resting state functional MRI; subjective cognitive decline (SCD); preclinical dementia; dynamic functional connectivity; dynamics; mdALFF; resting state functional MRI; subjective cognitive decline (SCD)

Subjective cognitive decline (SCD) appears in the preclinical stage of the Alzheimer's disease continuum. In this stage, dynamic features are more sensitive than static features to reflect early subtle changes in functional brain connectivity. Therefore, we studied local and extended dynamic co...