Telitacicept Following Plasma Exchange in the Treatment of Subjects With Recurrent NMOSD: Study Protocol for a Single-Center, Single-Arm, Open-Label Study

• Published in: Frontiers in neurology Vol. 12; p. 596791
• Main Authors: Ding, Jie, Cai, Yu, Deng, Ye, Jiang, Xianguo, Gao, Meichun, Lin, Yan, Zhao, Nan, Wang, Ze, Yu, Haojun, Lv, Wenwen, Zhang, Ying, Hao, Yong, Guan, Yangtai
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 18.03.2021
• Subjects: clinical study; effectiveness; Neurology; neuromyelitis optica spectrum disorders; plasma exchange; safety; telitacicept; clinical study; effectiveness; safety; telitacicept; study protocol; plasma exchange; neuromyelitis optica spectrum disorders

Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease that recurrently relapses and leads to severe disability. The available choices for disease prevention are few or intolerable. Previous studies suggested that telitacicept may provide a promising therap...