A sequence-based 163plex microhaplotype assay for forensic DNA analysis

• Published in: Frontiers in genetics Vol. 13; p. 988223
• Main Authors: Tao, Ruiyang, Yang, Qi, Xia, Ruocheng, Zhang, Xiaochun, Chen, Anqi, Li, Chengtao, Zhang, Suhua
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 05.10.2022
• Subjects: ancestry inference; forensic genetics; Genetics; microhaplotype (MH); mixture deconvolution; next-generation sequencing (NGS); microhaplotype (MH); mixture deconvolution; next-generation sequencing (NGS); ancestry inference; forensic genetics

Novel genetic marker microhaplotype has led to an upsurge in forensic genetic research. This study established a 163 microhaplotype (MH) multiplex assay based on next-generation sequencing (NGS) and evaluated the assay’s performance and applicability. Our results showed that the 163 MH assay was acc...