Therapeutic Potential of Exosomes in Pulmonary Fibrosis

• Published in: Frontiers in pharmacology Vol. 11; p. 590972
• Main Authors: Xie, Linshen, Zeng, Ye
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.12.2020
• Subjects: bone marrow mesenchymal stem cell; epithelial mesenchymal transition; exosome; myofibroblast; pulmonary fibrosis; Review; type II alveolar epithelial cell; epithelial mesenchymal transition; type II alveolar epithelial cell; myofibroblast; exosome; bone marrow mesenchymal stem cell; pulmonary fibrosis

Pulmonary fibrosis is closely associated with the recruitment of fibroblasts from capillary vessels with damaged endothelial cells, the epithelial mesenchymal transition (EMT) of type II alveolar epithelial cells, and the transformation of fibroblasts to myofibroblasts. Recent studies suggest that E...