Are CB2 Receptors a New Target for Schizophrenia Treatment?

• Published in: Frontiers in psychiatry Vol. 11; p. 587154
• Main Authors: Cortez, Isadora L, Rodrigues da Silva, Naielly, Guimarães, Francisco S, Gomes, Felipe V
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.10.2020
• Subjects: cannabinoids; dopamine; endocannabinoid system; microglia; Psychiatry; psychosis; cannabinoids; endocannabinoid system; dopamine; microglia; psychosis

Schizophrenia is a complex disorder that involves several neurotransmitters such as dopamine, glutamate, and GABA. More recently, the endocannabinoid system has also been associated with this disorder. Although initially described as present mostly in the periphery, cannabinoid type-2 (CB2) receptor...