N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients

• Published in: Frontiers in immunology Vol. 13; p. 827603
• Main Authors: Jalaleddine, Nour, Hachim, Mahmood, Al-Hroub, Hamza, Saheb Sharif-Askari, Narjes, Senok, Abiola, Elmoselhi, Adel, Mahboub, Bassam, Samuel Kurien, Nimmi Moni, Kandasamy, Richard K., Semreen, Mohammad H., Halwani, Rabih, Soares, Nelson C., Al Heialy, Saba
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.05.2022
• Subjects: COVID-19; Cresols; Humans; Immunology; Lysine; metabolomics; Metabolomics - methods; obesity; Obesity - complications; SARS-CoV-2; ultra-high-performance liquid chromatography-mass spectrometry; COVID-19; SARS-CoV-2; metabolomics; ultra-high-performance liquid chromatography-mass spectrometry; obesity

Despite the growing number of the vaccinated population, COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global health burden. Obesity, a metabolic syndrome affecting one-third of the population, has proven to be a major risk factor for COVID-19 severe...