Thromboelastometry (ROTEM®) in children: age-related reference ranges and correlations with standard coagulation tests

• Published in: British journal of anaesthesia : BJA Vol. 105; no. 6; pp. 827 - 835
• Main Authors: Oswald, E, Stalzer, B, Heitz, E, Weiss, M, Schmugge, M, Strasak, A, Innerhofer, P, Haas, T
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.12.2010; Oxford University Press
• Subjects: Adolescent; Aging - blood; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; blood; Blood Coagulation Tests - methods; Blood Specimen Collection - methods; blood, coagulation; Child; Child, Preschool; coagulation; Factor XIII - metabolism; Female; Fibrin - metabolism; Fibrinogen - metabolism; gender; Humans; Infant; Infant, Newborn; Male; measurement techniques; measurement techniques, thromboelastograph; Medical sciences; paediatrics; Reference Values; Reproducibility of Results; Sex Characteristics; Thrombelastography - methods; thromboelastograph; thromboelastometry; paediatrics; measurement techniques, thromboelastograph; gender; thromboelastometry; blood, coagulation; Human; measurement techniques; Measurement technique; Anesthesia; thromboelastograph; Child; blood; coagulation

The small sample volume needed and the prompt availability of results make viscoelastic methods like rotational thromboelastometry (ROTEM®) attractive for monitoring coagulation in small children. However, data on reference ranges for ROTEM® parameters in children are scarce. Four hundred and seven...