Altered expression of somatostatin signaling molecules and clock genes in the hippocampus of subjects with substance use disorder

• Published in: Frontiers in neuroscience Vol. 16; p. 903941
• Main Authors: Valeri, Jake, O’Donovan, Sinead M., Wang, Wei, Sinclair, David, Bollavarapu, Ratna, Gisabella, Barbara, Platt, Donna, Stockmeier, Craig, Pantazopoulos, Harry
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 07.09.2022
• Subjects: circadian; hippocampus; Neuroscience; sleep; somatostatin; substance use disorder; sleep; substance use disorder; circadian; hippocampus; somatostatin

Substance use disorders are a debilitating group of psychiatric disorders with a high degree of comorbidity with major depressive disorder. Sleep and circadian rhythm disturbances are commonly reported in people with substance use disorder and major depression and associated with increased risk of r...