Dynamic Changes in Myofibroblasts Affect the Carcinogenesis and Prognosis of Bladder Cancer Associated With Tumor Microenvironment Remodeling

• Published in: Frontiers in cell and developmental biology Vol. 10; p. 833578
• Main Authors: Du, YiHeng, Sui, YiQun, Cao, Jin, Jiang, Xiang, Wang, Yi, Yu, Jiang, Wang, Bo, Wang, XiZhi, Xue, BoXin
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.03.2022
• Subjects: bladder cancer; carcinogenesis; Cell and Developmental Biology; myofibroblasts; therapy responsiveness; tumor microenvironment; therapy responsiveness; tumor microenvironment; carcinogenesis; myofibroblasts; bladder cancer

Bladder cancer (BLCA) is a tumor that possesses significant heterogeneity, and the tumor microenvironment (TME) plays an important role in the development of BLCA. The TME chiefly consists of tumor cells and tumor-infiltrating immune cells admixed with stromal components. Recent studies have reveale...