SUMOylation Pattern Predicts Prognosis and Indicates Tumor Microenvironment Infiltration Characterization in Bladder Cancer

• Published in: Frontiers in immunology Vol. 13; p. 864156
• Main Authors: Xia, Qi-Dong, Sun, Jian-Xuan, Xun, Yang, Xiao, Jun, Liu, Chen-Qian, Xu, Jin-Zhou, An, Ye, Xu, Meng-Yao, Liu, Zheng, Wang, Shao-Gang, Hu, Jia
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.03.2022
• Subjects: bladder cancer; Female; Gene Expression Regulation, Neoplastic; Humans; Immunology; immunotherapy; Male; Prognosis; SUMOylation; tumor microenvironment; Tumor Microenvironment - genetics; tumor mutation burden; Urinary Bladder Neoplasms - pathology; SUMOylation; tumor microenvironment; tumor mutation burden; bladder cancer; immunotherapy

SUMOylation is an important component of post-translational protein modifications (PTMs), and bladder cancer (BCa) is the ninth most common cancer around the world. But the comprehensive role of SUMOylation in shaping tumor microenvironment (TME) and influencing tumor clinicopathological features an...