DEAD-Box Helicase 27 Triggers Epithelial to Mesenchymal Transition by Regulating Alternative Splicing of Lipoma-Preferred Partner in Gastric Cancer Metastasis

• Published in: Frontiers in genetics Vol. 13; p. 836199
• Main Authors: Jin, Yirong, Yang, Suzhen, Gao, Xiaoliang, Chen, Di, Luo, Tingting, Su, Song, Shi, Yanting, Yang, Gang, Dong, Lei, Liang, Jie
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.05.2022
• Subjects: alternative splicing; DDX27; EMT; gastric cancer metastasis; Genetics; LPP; gastric cancer metastasis; DDX27; alternative splicing; EMT; LPP

DEAD-box helicase 27 (DDX27) was previously identified as an important mediator during carcinogenesis, while its role in gastric cancer (GC) is not yet fully elucidated. Here, we aimed to investigate the mechanism and clinical significance of DDX27 in GC. Public datasets were analyzed to determine D...