Proteomic Profiling of Cryoglobulinemia

• Published in: Frontiers in immunology Vol. 13; p. 855513
• Main Authors: Liu, Peng, Wu, Jianqiang, Sun, Dandan, Li, Haolong, Qi, Zhihong, Tang, Xiaoyue, Su, Wei, Li, Yongzhe, Qin, Xuzhen
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 23.05.2022
• Subjects: Adiponectin; Apolipoproteins; biomarker; Biomarkers; Cryoglobulinemia - metabolism; cyroglobulinemia; Humans; Immunology; metabolic pathway; Proprotein Convertase 9 - metabolism; Proteome; proteomics; Proteomics - methods; serum; cyroglobulinemia; metabolic pathway; proteomics; biomarker; serum

We aimed to explore and identify candidate protein biomarkers of cryoglobulinemia (CGE) in disease control patients with negative cryoglobulin (DC) or healthy controls (HCs). The tandem mass tag (TMT)-labeled serum quantitative proteomics approach was used to identify differentially expressed protei...