Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia - Herta, Toni; Bhattacharyya, Aritra; Rosolowski, Maciej; Conrad, Claudia; Gurtner, Corinne; Gruber, Achim D.; Ahnert, Peter; Gutbier, Birgitt; Frey, Doris; Suttorp, Norbert; Hippenstiel, Stefan; Zahlten, Janine (Frontiers in immunology, 2021)
Keywords: Adult; Aged; Animals; Bacteremia - diagnosis; Bacteremia - pathology; Bronchoalveolar Lavage Fluid - cytology; Community-Acquired Infections - microbiology; Community-Acquired Infections - pathology; community-acquired pneumonia; Disease Models, Animal; Female; Humans; Immunology; innate immunity; Interleukin-10 - metabolism; Krueppel-like factor 4; Kruppel-Like Factor 4 - genetics; Kruppel-Like Factor 4 - metabolism; Lung - immunology; Lung - pathology; Male; Mice; Mice, Inbred C57BL; Middle Aged; myeloid cells; Phagocytes - metabolism; Pneumonia, Pneumococcal - immunology; Pneumonia, Pneumococcal - pathology; Severity of Illness Index; Streptococcus pneumoniae; Streptococcus pneumoniae - immunology; Krueppel-like factor 4; myeloid cells; innate immunity; community-acquired pneumonia; Streptococcus pneumoniae