Danggui-Shaoyao-San (DSS) Ameliorates Cerebral Ischemia-Reperfusion Injury via Activating SIRT1 Signaling and Inhibiting NADPH Oxidases

• Published in: Frontiers in pharmacology Vol. 12; p. 653795
• Main Authors: Luo, Yunxia, Chen, Hansen, Tsoi, Bun, Wang, Qi, Shen, Jiangang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 15.04.2021
• Subjects: Danggui-Shaoyao-San; oxidative stress; peroxynitrite; Pharmacology; SIRT1; stroke; peroxynitrite; SIRT1; stroke; Danggui-Shaoyao-San; oxidative stress

Danggui-Shayao-San (DSS) is a famous Traditional Chinese Medicine formula that used for treating pain disorders and maintaining neurological health. Recent studies indicate that DSS has neuroprotective effects against ischemic brain damage but its underlining mechanisms remain unclear. Herein, we in...