Hepatic Epigenetic Reprogramming After Liver Resection in Offspring Alleviates the Effects of Maternal Obesity

• Published in: Frontiers in cell and developmental biology Vol. 10; p. 830009
• Main Authors: Simino, Lais A de Paula, Fontana, Marina Figueiredo, de Fante, Thais, Panzarin, Carolina, Ignacio-Souza, Letícia Martins, Milanski, Marciane, Torsoni, Marcio Alberto, Desai, Mina, Ross, Michael G, Torsoni, Adriana Souza
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 31.03.2022
• Subjects: Cell and Developmental Biology; DOHaD; liver regeneration; metabolic programming; microRNAs; obesity; partial hepatectomy; microRNAs; partial hepatectomy; NAFLD; DOHaD; metabolic programming; liver regeneration; obesity

Obesity has become a public health problem in recent decades, and during pregnancy, it can lead to an increased risk of gestational complications and permanent changes in the offspring resulting from a process known as metabolic programming. The offspring of obese dams are at increased risk of devel...