Structural Characterization, Antimicrobial, Antibiofilm, Antioxidant, Anticancer and Acute Toxicity Properties of N-(2-hydroxyphenyl)-2-phenazinamine From Nocardiopsis exhalans (KP149558)

• Published in: Frontiers in cellular and infection microbiology Vol. 12; p. 794338
• Main Authors: Ramalingam, Vaikundamoorthy, Rajaram, Rajendran, Archunan, Govindaraju, Padmanabhan, Parasuraman, Gulyás, Balázs
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.05.2022
• Subjects: acute toxicity; Animals; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Anti-Infective Agents - chemistry; Anti-Infective Agents - toxicity; antibiofilm; anticancer; antimicrobial; antioxidant; Antioxidants - pharmacology; Biofilms; Cellular and Infection Microbiology; Escherichia coli; Microbial Sensitivity Tests; Nocardia; Nocardiopsis; Nocardiopsis exhalans; Zebrafish; antimicrobial; antioxidant; Nocardiopsis exhalans; antibiofilm; acute toxicity; anticancer

The present study aimed to isolate and identify potential drugs from marine actinomycete Nocardiopsis exhalans and screen them for biomedical applications. The cell-free culture of N. exhalans was extracted with ethyl acetate and the solvent extract showed six fractions in thin-layer chromatography....