Design and Evaluation of an Osteogenesis-on-a-Chip Microfluidic Device Incorporating 3D Cell Culture

• Published in: Frontiers in bioengineering and biotechnology Vol. 8; p. 557111
• Main Authors: Bahmaee, Hossein, Owen, Robert, Boyle, Liam, Perrault, Cecile M, Garcia-Granada, Andres A, Reilly, Gwendolen C, Claeyssens, Frederik
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 08.09.2020
• Subjects: additive manufacture; Bioengineering and Biotechnology; bioreactor; computational fluid dynamics; mechanotransduction; organ-on-a-chip; polyHIPE; tissue engineering; computational fluid dynamics; mechanotransduction; organ-on-a-chip; additive manufacture; bioreactor; polyHIPE

Microfluidic-based tissue-on-a-chip devices have generated significant research interest for biomedical applications, such as pharmaceutical development, as they can be used for small volume, high throughput studies on the effects of therapeutics on tissue-mimics. Tissue-on-a-chip devices are evolvi...