Causal effect of central obesity on left ventricular structure and function in preserved EF population: A Mendelian randomization study

• Published in: Frontiers in cardiovascular medicine Vol. 9; p. 1103011
• Main Authors: Gao, Yue, Zeng, Jiaxin, Zou, Fengwei, Zhang, Xinwei, Qian, Zhiyong, Wang, Yao, Hou, Xiaofeng, Zou, Jiangang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 09.01.2023
• Subjects: Cardiovascular Medicine; causal association; central obesity; left ventricular structure and function; Mendelian randomization; waist-to-hip ratio; left ventricular structure and function; causal association; central obesity; waist-to-hip ratio; Mendelian randomization

Observational studies have shown that central obesity is associated with adverse cardiac structure and function. However, causal association between central obesity and left ventricular (LV) structure and function in preserved ejection fraction (EF) population is still uncertain. Genome-wide associa...