Effects of papaverine and carbon dioxide alone or in combination on the blood flow of internal thoracic artery

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 132; no. 5; pp. 1126 - 1130
• Main Authors: Koramaz, Ismail, Ozkan, Mehmet, Altun, Gokalp, Guven, Kibar Yasar, Duman, Mine Kadioglu, Kalyoncu, Nuri Ihsan, Yaris, Ersin, Ozcan, Fahri
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Mosby, Inc 01.11.2006; AATS/WTSA; Elsevier
• Subjects: Aged; Biological and medical sciences; Carbon Dioxide - pharmacology; Female; Humans; Internal Mammary-Coronary Artery Anastomosis; Male; Mammary Arteries - drug effects; Medical sciences; Middle Aged; Papaverine - pharmacology; Regional Blood Flow; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Vasodilator Agents - pharmacology; CABG; 16; 17; ITA; Heart; Isoquinoline derivatives; Vasodilator agent; Carbon dioxide; Thorax; Blood flow; Alkaloid; Treatment; Antispasmodic agent; Surgery; Internal mammary artery; Hemodynamics; Papaverine

The internal thoracic artery is frequently used as an arterial graft for coronary bypass. Spasms of internal thoracic artery may contribute to early myocardial ischemia. To prevent vasospasm and increase the blood flow, some vasodilatory agents (such as carbon dioxide or papaverine) are used. The ai...