Acetylation at Lysine 86 of Escherichia coli HUβ Modulates the DNA-Binding Capability of the Protein

• Published in: Frontiers in microbiology Vol. 12; p. 809030
• Main Authors: Barlow, Victoria L., Tsai, Yu-Hsuan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.02.2022
• Subjects: DNA-binding protein; Escherichia coli; genetic code expansion; lysine acetylation; Microbiology; genetic code expansion; DNA-binding protein; lysine acetylation; HU; Escherichia coli

DNA-binding protein HU is highly conserved in bacteria and has been implicated in a range of cellular processes and phenotypes. Like eukaryotic histones, HU is subjected to post-translational modifications. Specifically, acetylation of several lysine residues have been reported in both homologs of E...