Risk factors for post-transplant relapse and survival in younger adult patients with t(8;21)(q22;q22) acute myeloid leukemia undergoing allogeneic hematopoietic stem cell transplantation: A multicenter retrospective study

• Published in: Frontiers in oncology Vol. 13; p. 1138853
• Main Authors: Zhou, Wei, Chen, Guofeng, Gong, Dan, Gao, Yi, Yu, Li
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 09.02.2023
• Subjects: acute myeloid leukemia; allogeneic hematopoietic stem cell transplantation; minimal residual disease; Oncology; relapse; RUNX1/RUNX1T1; t(8;21); minimal residual disease; acute myeloid leukemia; relapse; RUNX1/RUNX1T1; t(8;21); allogeneic hematopoietic stem cell transplantation
• ISSN: 2234-943X; 2234-943X
• DOI: 10.3389/fonc.2023.1138853

Outcomes of patients with t(8;21)(q22;q22) acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remain heterogeneous. To identify the risk factors for relapse and survival after allo-HSCT in t(8;21) AML patients, we retrospectively evaluated the clinical...