Ferroptosis Patterns and Tumor Microenvironment Infiltration Characterization in Bladder Cancer

• Published in: Frontiers in cell and developmental biology Vol. 10; p. 832892
• Main Authors: Xia, Qi-Dong, Sun, Jian-Xuan, Liu, Chen-Qian, Xu, Jin-Zhou, An, Ye, Xu, Meng-Yao, Liu, Zheng, Hu, Jia, Wang, Shao-Gang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 21.03.2022
• Subjects: bladder cancer; Cell and Developmental Biology; ferroptosis; immunotherapy; tumor microenvironment; tumor mutation burden; ferroptosis; tumor microenvironment; tumor mutation burden; bladder cancer; immunotherapy

Background: Ferroptosis is a unique iron-dependent form of cell death and bladder cancer (BCa) is one of the top ten most common cancer types in the world. However, the role of ferroptosis in shaping the tumor microenvironment and influencing tumor clinicopathological features remains unknown. Metho...