Expression profiles of melanogenesis-related genes and proteins in acquired melanocytic nevus

• Published in: Journal of cutaneous pathology Vol. 33; no. 3; pp. 207 - 215
• Main Authors: Hashimoto, Y., Ito, Y., Kato, T., Motokawa, T., Katagiri, T., Itoh, M.
• Format: Journal Article
• Language: English
• Published: Oxford, UK; Malden, USA Blackwell Publishing Ltd 01.03.2006; Blackwell
• Subjects: Biological and medical sciences; Biomarkers, Tumor - metabolism; Dermatology; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; gp100 Melanoma Antigen; Humans; Immunoenzyme Techniques; In Situ Hybridization; Intramolecular Oxidoreductases - genetics; Intramolecular Oxidoreductases - metabolism; Medical sciences; Melanocytes - metabolism; Melanocytes - pathology; Membrane Glycoproteins - genetics; Membrane Glycoproteins - metabolism; Microphthalmia-Associated Transcription Factor - genetics; Microphthalmia-Associated Transcription Factor - metabolism; Neoplasm Proteins - genetics; Neoplasm Proteins - metabolism; Nevus, Pigmented - genetics; Nevus, Pigmented - metabolism; Nevus, Pigmented - pathology; Oxidoreductases - genetics; Oxidoreductases - metabolism; Proteins - genetics; Proteins - metabolism; RNA, Messenger - analysis; Skin - metabolism; Skin - pathology; Skin Neoplasms - genetics; Skin Neoplasms - metabolism; Skin Neoplasms - pathology; Tumors of the skin and soft tissue. Premalignant lesions; Human; Immunohistochemistry; Anatomic pathology; Skin disease; Gene; Acquired; Dermatology; Melanogenesis; Melanocytic nevus; Protein

We used three types of AMN to investigate the expression profiles of melanogenesis‐related genes [tyrosinase, tyrosinase‐related protein‐1 (TRP1), dopachrome tautomerase (TRP2), Pmel‐17/gp100, P‐protein, and microphthalmia‐associated transcription factor (MITF)], as well as tyrosinase, TRP1, Pmel‐17...