ICOS-gene variants are not associated with atopic disease susceptibility in European children - Beier, Katja C.; Humberdros, Steffi; Witt, Heiko; Illi, Sabina; Rüschendorf, Franz; Nickel, Renate; Lee, Young-Ae; Lau, Susanne; Wahn, Ulrich; Hamelmann, Eckard (Pediatric allergy and immunology, 2009)
Keywords: Alleles; Allergens - immunology; allergic rhinitis; allergy; Antigens, Differentiation, T-Lymphocyte - genetics; Antigens, Differentiation, T-Lymphocyte - immunology; asthma; atopic dermatitis; atopy; Biological and medical sciences; Child; Chronic obstructive pulmonary disease, asthma; Cohort Studies; Europe - epidemiology; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Gene Frequency - genetics; Gene Frequency - immunology; General aspects; Genetic Predisposition to Disease - genetics; genetic variants; Genotype; Humans; Hypersensitivity - epidemiology; Hypersensitivity - genetics; Hypersensitivity - immunology; ICOS; ICOS, polymorphism; IgE; Inducible T-Cell Co-Stimulator Protein; Medical sciences; Pneumology; polymorphism; Promoter Regions, Genetic; Prospective Studies; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; single-nucleotide polymorphism; Europe; Allergy; Pediatrics; Skin disease; Nose disease; Genetic variability; Rhinitis; IgE; Atopy; Association; Immunology; Gene; Atopic dermatitis; ENT disease; Bronchus disease; Genetics; Obstructive pulmonary disease; Child; Human; Lung disease; Immunopathology; Respiratory disease; Genetic variant; Inducible costimulator; Genotype; Costimulatory molecule; Asthma; polymorphism; single-nucleotide polymorphism; genetic variants; Sensitivity; Single nucleotide polymorphism; allergy; atopy; IgE; asthma; atopic dermatitis; allergic rhinitis; ICOS