A Rare Case of Acute Infectious Purpura Fulminans Caused by Klebsiella Pneumoniae and Human Herpesvirus Type 5

• Published in: Journal of inflammation research Vol. 15; pp. 4251 - 4260
• Main Authors: Li, Xiao-Lan, Luan, Chun-Yan, Fan, Ying-Jun, Lin, Xiao-Ying, Jiang, Dong, Su, Mei-Xian, Wang, Gang, Yang, Xu
• Format: Journal Article
• Language: English
• Published: Macclesfield Dove Medical Press Limited 31.07.2022; Taylor & Francis Ltd; Dove; Dove Medical Press
• Subjects: acute infectious purpura fulminans; Analgesics; Antithrombin; Bacteria; Bacterial infections; Bacterial pneumonia; Blood clot; Blood pressure; Blood tests; Blood vessels; Case Report; Case reports; Computed tomography; Dermatology; Disseminated intravascular coagulation; Drug resistance; Embolisms; Fever; Genetic screening; Health aspects; Hemorrhage; human herpesvirus type 5; Inflammation; Intubation; klebsiella pneumoniae; Laboratories; Liver; multiple organ and system failures; Necrosis; Occlusion; Oxygen saturation; Pneumonia; Protein C; Protein deficiency; Proteins; Pulmonary arteries; Purpura; Purpura (Pathology); Secretions; Sepsis; Skin; Skin diseases; Skin lesions; Sputum; Thrombocytopenia; Thrombosis; Veins & arteries; Viral infections; Virus diseases; China

Background: Purpura fulminans (PF), a rare, life-threatening disorder, is a hematological emergency in which there is skin necrosis, disseminated intravascular coagulation (DIC), and protein C deficiency. In PF, the skin necrosis and DIC are secondary to protein C deficiency. This may progress rapid...