Efficacy and tolerability of tiapamil in patients with mild to moderate essential hypertension

• Published in: Journal of cardiovascular pharmacology Vol. 14; no. 1; p. 166
• Main Authors: Lacourcière, Y, Carrier, M, Toal, C B
• Format: Journal Article
• Language: English
• Published: United States 01.07.1989
• Subjects: Adult; Aged; Blood Pressure - drug effects; Calcium Channel Blockers - adverse effects; Calcium Channel Blockers - therapeutic use; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate - drug effects; Humans; Hypertension - drug therapy; Hypertension - physiopathology; Male; Middle Aged; Propylamines - adverse effects; Propylamines - therapeutic use; Random Allocation; Tiapamil Hydrochloride

Although early experience with tiapamil, a new calcium antagonist structurally related to verapamil, showed good antihypertensive efficacy and minimal adverse effects, recent studies have shown conflicting results. This single-blind dose-titration study was designed to determine the therapeutic effi...