Dietary supplementation of 25-hydroxycholecalciferol improves cardiac function and livability in broiler breeder hens–amelioration of blood pressure and vascular remodeling

• Published in: Poultry science Vol. 99; no. 7; pp. 3363 - 3373
• Main Authors: Yeh, Yo-Lin, Chou, Pao-Chia, Chen, Yu-Hui, Lai, Lih-Shiuh, Chung, Thau Kiong, Walzem, Rosemary L., Huang, San-Yuan, Chen, Shuen-Ei
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.07.2020; Elsevier
• Subjects: 25-hydroxycholecalciferol; Animal Feed - analysis; Animals; antihypertensive effect; blood pressure; Blood Pressure - drug effects; broiler breeder hen; broiler breeders; Calcifediol - administration & dosage; Calcifediol - metabolism; cardiac hypertrophy; cardiac output; cell proliferation; Chickens; collagen; death; Diet - veterinary; dietary supplements; Dietary Supplements - analysis; elastin; feed intake; Genetics and Molecular Biology; heart rate; hypertension; hypertrophy; hypoxia; mortality; nitric oxide; pathogenesis; pulmonary artery; Random Allocation; renin-angiotensin system; restricted feeding; smooth muscle; vascular remodeling; Vascular Remodeling - drug effects; Vitamins - administration & dosage; Vitamins - metabolism; broiler breeder hen; 25-hydroxycholecalciferol; cardiac hypertrophy; vascular remodeling; hypertension

A supplement of 69 μg 25-hydroxycholecalciferol (25-OH-D3)/kg feed suppressed the mortality in feed-restricted broiler breeder hens and in hens allowed ad libitum feed intake (Ad-hens) in a feeding trial from age 26 to 60 wk. Outcomes for the mechanisms found that 25-OH-D3 relieved systemic hypoxia,...