Are All Commonly Prescribed Antipsychotics Associated with Greater Mortality in Elderly Male Veterans with Dementia?

• Published in: Journal of the American Geriatrics Society (JAGS) Vol. 58; no. 6; pp. 1027 - 1034
• Main Authors: Rossom, Rebecca C., Rector, Thomas S., Lederle, Frank A., Dysken, Maurice W.
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.06.2010; Wiley Subscription Services, Inc
• Subjects: Aged; Aged, 80 and over; Antipsychotic Agents - administration & dosage; Antipsychotic Agents - adverse effects; antipsychotics; Benzodiazepines - administration & dosage; Benzodiazepines - adverse effects; Cohort Studies; Comorbidity; Dementia; Dementia - drug therapy; Dementia - mortality; Dibenzothiazepines - administration & dosage; Dibenzothiazepines - adverse effects; elderly; Female; Haloperidol - administration & dosage; Haloperidol - adverse effects; Humans; Male; Mortality; Older people; Proportional Hazards Models; Psychotropic drugs; Quetiapine Fumarate; Retrospective Studies; Risk Factors; Risperidone - administration & dosage; Risperidone - adverse effects; Sex Factors; Veterans

OBJECTIVES: To estimate mortality risk associated with individual commonly prescribed antipsychotics. DESIGN: Five‐year retrospective study. SETTING: Veterans national healthcare data. PARTICIPANTS: Predominantly male, aged 65 and older, with a diagnosis of dementia and no other indication for an an...