MUC2 expression in primary mucinous and nonmucinous adenocarcinoma of the prostate: an analysis of 50 cases on radical prostatectomy

• Published in: Modern pathology Vol. 21; no. 7; pp. 789 - 794
• Main Authors: Osunkoya, Adeboye O, Adsay, N Volkan, Cohen, Cynthia, Epstein, Jonathan I, Smith, Stacey L
• Format: Journal Article
• Language: English
• Published: New York Elsevier Inc 01.07.2008; Nature Publishing Group US; Elsevier Limited
• Subjects: Adenocarcinoma, Mucinous - metabolism; Adenocarcinoma, Mucinous - pathology; Adenocarcinoma, Mucinous - surgery; Adult; Aged; Biomarkers, Tumor - metabolism; Humans; Immunoenzyme Techniques; Laboratory Medicine; Male; Medicine; Medicine & Public Health; Middle Aged; MUC2; Mucin-2; mucinous adenocarcinoma; Mucins - metabolism; nonmucinous adenocarcinoma; original-article; Pancreas; Pathology; Prostate - anatomy & histology; Prostate - metabolism; Prostate cancer; Prostatectomy; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Prostatic Neoplasms - surgery; Stains & staining; Tumors; Atlanta Georgia; United States > US; mucinous adenocarcinoma; MUC2; nonmucinous adenocarcinoma

The expression of mucin (MUC2) in prostate cancer has not been well studied previously and may be of prognostic and pathobiologic significance. It is, however, well known that MUC2 expression in mucinous pancreatic and breast cancer represents an indolent pathway since these tumors have a significan...