Wound healing of nanofiber comprising Polygalacturonic/Hyaluronic acid embedded silver nanoparticles: In-vitro and in-vivo studies

• Published in: Carbohydrate polymers Vol. 238; p. 116175
• Main Authors: El-Aassar, M.R., Ibrahim, Omar M., Fouda, Moustafa M.G., El-Beheri, Nagham G., Agwa, Mona M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.06.2020
• Subjects: albino; Animals; Anti-Bacterial Agents - pharmacology; Antibacterial; antimicrobial properties; antioxidant activity; bacteria; Bacteria - drug effects; Bandages; contact angle; Fourier transform infrared spectroscopy; histopathology; Hyaluronic acid; Hyaluronic Acid - chemistry; in vivo studies; Male; Metal Nanoparticles - therapeutic use; Nanofiber; nanofibers; Nanofibers - therapeutic use; nanosilver; Pectins - chemistry; physical activity; Polygalacturonic acid; Rats; scanning electron microscopy; Silver - chemistry; Silver - pharmacology; Silver nanoparticles; thermal analysis; tissue repair; transmission electron microscopy; ultraviolet-visible spectroscopy; Wound dressing; Wound Healing - drug effects; Nanofiber; Wound dressing; Antibacterial; Hyaluronic acid; Polygalacturonic acid; Silver nanoparticles

•Novel wound dressing, of Polygalacturonic, Hyaluronic acid embedded silver nanoparticles is provided.•Electrospinning is used to fabricated the previous wound dressing formulation.•The nanofiber embedded AgNPs was applied to the wounded site of albino rats in-vivo.•Antimicrobial activity for the na...