Integrated neutrophil-to-lymphocyte ratio and handgrip strength better predict survival in patients with cancer cachexia

• Published in: Nutrition (Burbank, Los Angeles County, Calif.) Vol. 122; p. 112399
• Main Authors: Zhang, Kai-Lun, Zhou, Ming-Ming, Wang, Kun-Hua, Weng, Min, Zhou, Fu-Xiang, Cui, Jiu-Wei, Li, Wei, Ma, Hu, Guo, Zeng-Qing, Li, Su-Yi, Chen, Jun-Qiang, Wu, Xiang-Hua, Zhao, Qing-Chuan, Li, Ji-Peng, Xu, Hong-Xia, Shi, Han-Ping, Song, Chun-Hua
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2024; Elsevier Limited
• Subjects: Blood; Body mass index; Cachexia; Cachexia - etiology; Cancer; Cancer cachexia; Clinical outcomes; Cohort Studies; confidence interval; Confidence intervals; death; Evaluation; Female; Females; Hand Strength; Handgrip strength; hazard ratio; Humans; Inflammation; Leukocytes (neutrophilic); Lymphocytes; Male; Males; Malnutrition; Medical prognosis; mortality; Muscle strength; Musculoskeletal system; Neoplasms - complications; Neutrophil-to-lymphocyte ratio; Neutrophils; Nutrition; Patients; Physiology; Prognosis; Prognostic; Quality of life; Questionnaires; Regression analysis; Regression models; Retrospective Studies; risk; Serology; Skeletal muscle; Statistical analysis; Survival; Tumors; China; Cancer cachexia; Handgrip strength; Malnutrition; Neutrophil-to-lymphocyte ratio; Prognostic

•The NH index combined with NLR and HGS is an effective predictor of the prognosis of patients with cancer cachexia.•The study was conducted on a multicenter observational cohort with a large sample, which enhances the credibility, reliability, and representativeness of our results.•The study can of...