A systematic review and meta-analysis of the cardioprotective effects of remote ischaemic preconditioning in open cardiac surgery

• Published in: Journal of the Royal Society of Medicine Vol. 105; no. 10; pp. 436 - 445
• Main Authors: Pilcher, Janine M, Young, Paul, Weatherall, Mark, Rahman, Ishtiaq, Bonser, Robert S, Beasley, Richard W
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.10.2012; Royal Society of Medicine Press
• Subjects: Biological and medical sciences; Cardiac Surgical Procedures - methods; Coronary Artery Bypass - methods; Double-Blind Method; General aspects; Humans; Ischemic Preconditioning - methods; Medical sciences; Myocardial Reperfusion Injury - etiology; Myocardial Reperfusion Injury - prevention & control; Postoperative Complications - prevention & control; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Thoracic Surgery - methods; Troponin - metabolism; Medicine; Ischemia; Cardioprotective agent; Cardiovascular disease; Systematic review; Cardiac surgery; Preconditioning; Metaanalysis

Objective To investigate the cardioprotective efficacy of remote ischaemic preconditioning (RIPC) in cardiac surgery. Design We have performed a systematic search of MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials to identify randomized controlled trials involving RIPC. Setting Ra...