Screening for Fragile X Syndrome Among Filipino Children with Autism Spectrum Disorder

• Published in: Journal of autism and developmental disorders Vol. 53; no. 11; pp. 4465 - 4473
• Main Authors: Dy, Angel Belle C., Tanchanco, Lourdes Bernadette S., Sy, Jenica Clarisse Y., Levantino, Myla Dominicina, Hagerman, Randi J.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.11.2023; Springer; Springer Nature B.V
• Subjects: Adaptive behavior; Adjustment (to Environment); Autism; Autism Spectrum Disorders; Autistic children; Behavior Rating Scales; Behavioral Science and Psychology; Carriers; Child and School Psychology; Child development; Children; Clinical assessment; Complications and side effects; Congenital Impairments; Demographic aspects; Deoxyribonucleic acid; Diagnosis; DNA; DNA methylation; Foreign Countries; Fragile X syndrome; Functional magnetic resonance imaging; Genetic Disorders; Genetics; High risk; Intellectual disabilities; Intellectual Disability; Medical diagnosis; Medical Evaluation; Medical screening; Methods; Mosaicism; Mutation; Neurosciences; Original Paper; Pediatrics; Pervasive developmental disorders; Philippino; Physical examinations; Polymerase chain reaction; Psychology; Public Health; Risk factors; Risk groups; Screening Tests; Tests; Young Children; Philippines; Autism; Screening; Fragile X syndrome; Genetic testing; Autism spectrum disorder

Individuals with autism spectrum disorder present with difficulties in social communication, restricted interests or behaviors and other co-morbidities. About 2 to 10% of cases of autism have a genetic cause, and Fragile X Syndrome (FXS) is reported in 0 to 6.5% of individuals with autism. However,...