Kynurenine and uric acid levels in chronic myeloid leukemia patients - Vonka, Vladimir; Humlova, Zuzana; Klamova, Hana; Kujovska-Krcmova, Lenka; Petrackova, Martina; Hamsikova, Eva; Krmencikova-Fliegl, Monika; Duskova, Martina; Roth, Zdenek (Oncoimmunology, 2015)
Keywords: 3-dioxygenase; chronic myeloid leukemia; CML, chronic myeloid leukemia; IDO, indoleamine 2, 3-dioxygenase; indoleamine 2; INFα, interferon- α; INFγ, interferon-γ; KTI, kynurenine/tryptophan index; KYN, kynurenine; kynurenine; NK, natural killer; Original Research; PBMC, peripheral blood mononuclear cells; Philadelphia chromosome positive; T regs, regulatory T cells; TDO, tryptophan 2, 3-dioxygenase; TKI, tyrosine-kinase inhibitors; TRY, tryptophan; tryptophan metabolism; UA, uric acid; uric acid; CML, chronic myeloid leukemia; IDO, indoleamine 2, 3-dioxygenase; Ph+, Philadelphia chromosome positive; tryptophan metabolism; TRY, tryptophan; PBMC, peripheral blood mononuclear cells; INFγ, interferon-γ; kynurenine; 3-dioxygenase; INFα, interferon- α; KTI, kynurenine/tryptophan index; KYN, kynurenine; TDO, tryptophan 2, 3-dioxygenase; indoleamine 2; UA, uric acid; TKI, tyrosine-kinase inhibitors; NK, natural killer; T regs, regulatory T cells; chronic myeloid leukemia; uric acid