Development of a SARS-CoV-2 Vaccine Candidate Using Plant-Based Manufacturing and a Tobacco Mosaic Virus-like Nano-Particle - Royal, Joshua M.; Simpson, Carrie A.; McCormick, Alison A.; Phillips, Amanda; Hume, Steve; Morton, Josh; Shepherd, John; Oh, Youngjun; Swope, Kelsi; DeBeauchamp, Jennifer L.; Webby, Richard J.; Cross, Robert W.; et al. (Vaccines (Basel), 2021)
Keywords: ACE2; Angiotensin-converting enzyme 2; Antigens; Binding; Chromatography; Coronaviruses; COVID-19; COVID-19 vaccines; CpG islands; Disease transmission; Epitopes; Fatalities; Glycoproteins; Humidity; Immunogenicity; Immunoglobulin G; Infections; Influenza; Lymphocytes T; Manufacturing; Monoclonal antibodies; nanoparticle; Nanoparticles; Neutralizing; Pandemics; Pathogens; Peptides; plant-based manufacturing; Proteins; receptor-binding domain; Receptors; Respiratory diseases; SARS-CoV-2 vaccine; Severe acute respiratory syndrome coronavirus 2; Spike glycoprotein; Spike protein; Tobacco; Transmission electron microscopy; Vaccines; Viral diseases; Viruses; United States--US