FOXD1 Repression Potentiates Radiation Effectiveness by Downregulating G3BP2 Expression and Promoting the Activation of TXNIP-Related Pathways in Oral Cancer

• Published in: Cancers Vol. 12; no. 9; p. 2690
• Main Authors: Lin, Che-Hsuan, Lee, Hsun-Hua, Chang, Wei-Min, Lee, Fei-Peng, Chen, Lung-Che, Lu, Long-Sheng, Lin, Yuan-Feng
• Format: Journal Article
• Language: English
• Published: MDPI AG 21.09.2020; MDPI
• Subjects: Gene expression; Genetic aspects; Health aspects; Mouth cancer; Taiwan

Radiotherapy is commonly used to treat oral cancer patients in the current clinics; however, a subpopulation of patients shows poor radiosensitivity. Therefore, the aim of this study is to identify a biomarker or druggable target to enhance the effectiveness of radiotherapy on oral cancer patients....