Facilitating the mineralization of oligo(poly(ethylene glycol) fumarate) hydrogel by incorporation of hydroxyapatite nanoparticles

• Published in: Journal of biomedical materials research. Part A Vol. 100A; no. 5; pp. 1316 - 1323
• Main Authors: Nejadnik, M. Reza, Mikos, Antonios G., Jansen, John A., Leeuwenburgh, Sander C. G.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.05.2012; Wiley-Blackwell
• Subjects: Animals; Biological and medical sciences; Body Fluids - chemistry; bone regeneration; Calcium - metabolism; Cattle; Cell physiology; composite; Durapatite - chemistry; Fumarates - chemistry; Fundamental and applied biological sciences. Psychology; Gelatin - chemistry; hydrogel; Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry; hydroxyapatite nanoparticles; Medical sciences; mineralization; Mineralization, calcification; Minerals - chemistry; Molecular and cellular biology; Nanoparticles - chemistry; Nanoparticles - ultrastructure; Orthopedic surgery; Polyethylene Glycols - chemistry; Spectroscopy, Fourier Transform Infrared; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology. Biomaterials. Equipments; Time Factors; X-Ray Diffraction; Incorporation; Nanoparticle; Bone regeneration; Hydroxyapatite; hydroxyapatite nanoparticles; Composite material; Ethylene oxide polymer; Cyclic ether polymer; Mineralization; composite; Biomaterial; Hydrogel; Biomedical engineering

Exploring strategies to induce the mineralization of hydrogels is an important step toward the development of hydrogel‐based materials for bone regeneration. In the current study, the effect of incorporating hydroxyapatite (HA) nanoparticles on the mineralization capacity of an inert poly(ethylene g...