Comparative Analysis of PRAME Expression in 127 Acral and Nail Melanocytic Lesions

• Published in: The American journal of surgical pathology Vol. 46; no. 5; p. 579
• Main Authors: Santandrea, Giacomo, Valli, Riccardo, Zanetti, Eleonora, Ragazzi, Moira, Pampena, Riccardo, Longo, Caterina, Lai, Michela, Piana, Simonetta, Cesinaro, Anna M
• Format: Journal Article
• Language: English
• Published: United States 01.05.2022
• Subjects: Antigens, Neoplasm - analysis; Diagnosis, Differential; Humans; Male; Melanocytes - pathology; Melanoma - pathology; Nevus, Epithelioid and Spindle Cell - pathology; Reproducibility of Results; Skin Neoplasms - pathology

PRAME (PReferentially expressed Antigen in MElanoma), a cancer testis antigen expressed in low levels in gonadal, endometrial, and adrenal gland tissues, has been recently considered a valuable tool in the differential diagnosis between benign and malignant melanocytic lesions. The aim of the curren...