The Anticariogenic Effect of Sugar-Free Gum Containing CPP-ACP Nanocomplexes on Approximal Caries Determined Using Digital Bitewing Radiography

• Published in: Caries research Vol. 42; no. 3; pp. 171 - 184
• Main Authors: Morgan, M.V., Adams, G.G., Bailey, D.L., Tsao, C.E., Fischman, S.L., Reynolds, E.C.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.01.2008
• Subjects: Adolescent; Cariostatic Agents - therapeutic use; Caseins - therapeutic use; Chewing Gum - analysis; Child; Dental Caries - diagnostic imaging; Dental Caries - prevention & control; Disease Progression; Double-Blind Method; Female; Humans; Logistic Models; Male; Odds Ratio; Original Paper; Radiography, Bitewing; Radiography, Dental, Digital; Sample Size; Sorbitol; Sweetening Agents; Tooth Remineralization - methods; Approximal caries progression; Randomized clinical trial; Sugar-free chewing gum; Digital bitewing radiography; Ordinal categorical data; Casein phosphopeptide-amorphous calcium phosphate nanocomplexes; Enamel remineralization

This study investigated, using digital bitewing radiography, the progression and regression of approximal caries in adolescent subjects chewing a sugar-free gum containing 54 mg CPP-ACP relative to the identical gum without CPP-ACP. 2,720 subjects from 29 schools were randomly assigned to one of the...