Cochlear implants: Causes, effects and mitigation strategies for the foreign body response and inflammation

• Published in: Hearing research Vol. 422; p. 108536
• Main Authors: Rahman, Muhammad T., Chari, Divya A., Ishiyama, Gail, Lopez, Ivan, Quesnel, Alicia M., Ishiyama, Akira, Nadol, Joseph B., Hansen, Marlan R.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2022
• Subjects: Animals; Biomaterials; Cochlea - physiology; Cochlear implant; Cochlear Implantation - methods; Cochlear Implants; Fibrosis; Foreign body response; Hearing Loss, Sensorineural; Humans; Inflammation; Cochlear implant; Foreign body response; Inflammation; Fibrosis; Biomaterials

•Foreign body response (FBR) following cochlear implantation affects the residual hearing and efficiency of cochlear implant.•Cellular, molecular, anatomical, and systemic aspects of foreign body response following cochlear implantation in human subjects, animal models and in vitro has been reviewed...